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A blood test that can accurately predict whether a child is likely to develop a life-threatening illness could be on the horizon, according to researchers at Children's National Hospital.
In a study funded by the National Institutes of Health, the hospital's Division of Pediatric Infectious Diseases analyzed 416 blood samples from 237 patients, 141 of whom had Multisystem Inflammatory Syndrome in Children (MIS-C) and 70 of whom had acute COVID-19 infection, the Washington Post reports.
Researchers found that while multiple inflammatory pathways were activated in both cases, there were specific patterns that were unique to each disease and distinguish them from mild COVID and other control conditions.
"Our overall goal is to develop tests that can accurately predict if a child with COVID is likely to develop severe disease, and also accurately distinguish children with MIS-C from children with other causes of fever," says a co-author of the study, published in Cell Reports Medicine.
"These two groups of children can decompensate quickly and require rapid diagnosis and more aggressive treatments right from the beginning," she adds.
The Post reports MIS-C occurs when different parts of the body, including skin, mucous membranes, gastrointestinal tract, heart, lungs, kidneys, or brain, become inflamed after a CO
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