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"A vast majority of our patients not only responded to the therapy, but they were able to come off their antivirals, which come with extensive side effects," says Michael Keller, the paper's first author and the Translational Research Laboratory director at the Children's National Cell Enhancement and Technologies for Immunotherapy (CETI) program.
In a first-of-its-kind clinical trial, researchers found that therapies made from virus-specific T-cells can effectively treat immunocompromised pediatric patients, far surpassing the current standard of care, according to Nature Communications.
More than 60% of patients in the phase 2 clinical trial led by investigators from Children's National Hospital and Huntsman Cancer Institute responded to the innovative therapy.
This new treatment uses blood from healthy donors to manufacture a highly specialized immune therapy that, when given to immune-compromised patients, prompts their immune system to fight off potentially life-threatening viruses, including cytomegalovirus, Epstein-Barr infections, and adenovirus.
Without this therapy, estimates suggest that less than 30% of patients would recover, using standard protocols.
Children's National is one of a handful of hospitals in the US that uses this approach, and the study includes critically ill patients who are often excluded from research.
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A customized collection of grant news from foundations and the federal government from around the Web.
Schools have largely been spared Disruptive Innovation of the sort that has transformed everything from retail to consumer package goods, telecommunications, computing, steel, newspapers, and...more
The R21/Matrix-M vaccine will first be deployed in 19 priority health districts across five regions.The best individual protection for children under five combines vaccination, seasonal malaria...more
The Eddies is a nonprofit that brings innovators together.It was rebranded back in twenty-eighteen and through mass Innovation became a nonprofit.Joanna and Kelly are the founders of Joanna's, a...more
Relational identity and organizational identity jointly played a chain mediating role between inclusive leadership and the innovative behavior of female employees with two children.The organizational...more
Schneider Electric highlights AI-driven growth, data centre demands, and sustainability ahead of Computex 2025 launch.Schneider Electric discussed AI's rapid growth and its demand for electricity,...more
Mary Ann Wolf is president and executive director of the Public School Forum of North Carolina.Wolf: In local public schools across North Carolina, millions of students receive breakfast and lunch at...more
Oti - the Israeli Autism Association, is advancing the development of children and adults on the autism spectrum.Recent years have witnessed a profound transformation in our understanding of autism...more
COPEMA seeks to mobilise parliamentary support to increase domestic funding and ensure effective implementation of malaria control strategies.The disease accounts for approximately 600,000 deaths...more
MP Tourism Unveils Immersive Zone at KidZania Showcasing the State's Top Attractions.The Madhya Pradesh Tourism Experience Center was officially inaugurated at Kid Zania Mumbai.The initiative is...more
The Momentum Spine App enables radiation-free assessment and provides digital models of the patient's spine.The smartphone app technology starts with parents taking videos of their children at home...more
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